Chlamydia pneumoniae / 12

Hahn DL, Kern DG, Neill MA
Chest 1994; 105:1914-1915*
The microimmunofluorescence (MIF) test remains the “gold standard” to measure C. pneumoniae antibodies. Nevertheless, there has been controversy about the accuracy of MIF serodiagnostic criteria for diagnosing acute infection (including incomplete recognition of the possibility of persistent infection unaccompanied by an acute antibody response), and debate about appropriate methods to measure population seroprevalence. This letter highlights some of the issues.

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